The evil Dr. Zin has genetically modified household pests into disturbingly large insects that he calls assassinoids, fearless and devoted warriors that will carry out his plan for world domination. Team Quest, headed by internationally respected scientist Benton Quest, is Earth's only hope. When the good doctor becomes Zin's captive, the stakes -- and the action quotient -- grow higher. Enter Jonny Quest, Dr. Quest's bright, excitable, imaginative and heroic young son, ex-special agent Race Bannon, Jonny's child genius pals Hadji and Jessie (Race's daughter), their robotic pal 4-DAC and bulldog Bandit to complete the job of vermin extermination before it's too late.

In this animated feature, Jonny Quest heads off on yet another exciting adventure. This time, Jonny and company must stop a crazed doctor from using weather satellites and voracious, genetically-engineered insects to take over the world.