Famous concert pianist Vernon Paris' (James Stapleton) hands are crushed in a car accident. An ambitious doctor (Paul Lukather) grafts new hands on him in a revolutionary experimental operation. Unbeknownst to Paris, these hands belonged to a killer and they begin to take over his life, forcing him to commit heinous acts and murder. A chilling remake of the classic horror tale Hands Of Orlac, this grippng version is ghastly in its nightmarish tone as the pianist's sanity unravels and his evil hands become uncontrollable.

When a pianist's hands are destroyed he receives a transplant of human hands, (once belonging to a murder victim.) Much to the bewilderment of the pianist, these new hands decide to take control and gain vengeance for their past owner's death. See "Hands of Orlac" for an interesting comparison.