After the wealthy Flying U Ranch owner Sam Talbot is killed by a fall from a horse, reporter Connie Edwards (Dale Evans) enlists the help of newspaper editor Roy Rogers to investigate a rumor that Sam may have actually been murdered. Talbot's 12 year-old ward, Duke Lowery (Lanny Rees), inherits Sam's ranch, much to the dismay of Talbot's greedy niece, Jan Holloway (Carol Hughes). Roy, Dale and ranch hand Gabby (Gabby Hayes) set out to prove Jan is involved in a threat on Duke's life and possibly Sam's murder. Under the superb direction of William Witney, Home in Oklahoma is filled with memorable songs, including Roy and Dale's rendition of the novelty classic "Miguelito."

Roy Rogers and Dale Evans team up in another music-filled, action-packed western. Here, Dale plays Connie Evans, a city reporter from St. Louis who travels to Oklahoma to investigate the death--possibly a murder--of ranch owner Sam Talbot. Roy plays a local newspaper editor, and the two work together to ensure that young Duke Lowery (Lanny Rees) receives the ranch intended as his inheritance and to uncover the perpetrators of the terrible crime. Like most Roy Rogers westerns, this film features music by Sons of the Pioneers, as well as the Flying "L" Ranch Quartet.