After his Los apartment is robbed, selfish hedonist Rick (Jake Busey) flies off the handle and leaves behind his loyal girlfriend Tamara (Natasha Lyonne) and his best friend Jack (Adam Goldberg) in favor of a hedonistic road trip. He begins in Los Angeles, where he acquires a sidekick in the more reserved Jules (Crispin Glover). In Palm Springs, he has spends a brief, educational experience with his favorite porn star, Ginger (Jennifer Tilly). Through various intoxicating beverages and substances, Rick and Jules learn a little bit about themselves, their lives, and each other. Based on the 1993 novel by Bruce Craven, who co-wrote the screenplay.